Obesity and Multiple Sclerosis Susceptibility: A Review

Association between Tumor Necrosis Factor- α-308 G/A Polymorphism and Multiple Sclerosis: A Systematic Review and Meta-Analysis

Multiple sclerosis (MS) is a complex polygenic disease in which gene-environment interactions are important. A number of studies have investigated the association between tumor necrosis factor-α (TNF-α) -308 G/A polymorphism (substitution G→A, designated as TNF1 and TNF2) and MS susceptibility in different populations, but the results of individual studies have been inconsistent. Therefore, per...

Association of Apolipoprotein E Polymorphism with Susceptibility to Multiple Sclerosis

Association of CD24V/V Genotype with Susceptibility and Progression of Multiple Sclerosis in Iranian Population

A single nucleotide polymorphism (SNP) in CD24 has been associated with multiple sclerosis (MS) in a population based study. This SNP results in the replacement of alanine (CD24A) by valine (CD24V) at amino acid 57 in the resulting polypeptide chain. In the current study, the genotyping of this SNP and its contribution to MS in 217 patients and 200 healthy individuals of an Iranian population w...

Effects of Meat Consumption on Multiple Sclerosis: A Systematic Review and Meta-analysis

Backgrounds and Objectives: Multiple sclerosis is a common cause of neurological disabilities worldwide. Diet is a potential risk factor for the pathogenesis of multiple sclerosis  and dietary intervention can be used as a prevention method for multiple sclerosis. The purpose of this study was the investigation of relationships between the type of meat consumed by the patients and multiple scle...

Immunomodulatory Effect of Mesenchymal Stem Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: A Review Study

Multiple Sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system that may lead to disability of the patient. Current MS treatment regimens are still insufficient and research is conducted for developing more effective therapies capable of targeting neurodegeneration, inflammation, and demyelination. Recent results of experimental and clinical studies in ...